Though they don't change in appearance, the Charm/Shield will change in name (modifiers remain - thanks for reminding me, ) as more accessories are added. If you made a charm with the Vitamins and Armor Polish, you can later add the Adhesive Bandage to it to get that immunity too. What that means is you can add any other component accessories to either the Charm or Shield, and it'll automatically add that debuff immunity in.
Added to both those items' tooltips is a short note: 'Can be upgraded with certain accessories.' Now, you can combine any two (or more) of these eleven, OR one of the double accessories (Armor Bracing, etc.) with another component, to produce an Ankh Charm, which can then be used as normal to make the Ankh Shield. But those are so rare, you say! Well, that's okay.